Everyday Health Additional Dosage Information Theres no recommended dietary allowance for biotin. J Nutr 2002;132:3405-10. 2002;75:179-80. View abstract. Since 1935 King Cole have supplied high quality hand knitting yarns and wools. View abstract. Available at: https://books.nap.edu/books/0309065542/html/. Rocklin, CA: Prima Publishing; 1998. We'll assume you're ok with this, but you can opt-out if you wish. Expert.Rev.Endocrinol.Metab 11-1-2008;3(6):715-724. Hook size. There is no limit on how much biotin you can take and there is no evidence that it causes harm, even at very high doses. All rights reserved. 25% Cotton. J Nutr.Biochem. I take vitamins about every other day but just recently I have started taking folic acid to prepare myself for having children. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. A lack of biotin is rare. However, if it occurs it may lead to skin rash, loss of hair, high blood levels of cholesterol, and heart problems. View abstract. Didn't find the answer you were looking for? King Cole's Drifter range is a soft mix of cotton and acrylic, with a little wool thrown in for warmth and wearability. Drifter Super Soft Double Knit from King Cole. Bumps in the genital area might be STDs, but are usually not serious. Follow your healthcare provider's instructions. J Appl Lab Med. Breast cancer is not usually painful. This content does not have an Arabic version. It's soft and colourful, perfect for blankets, accessories, housewares, and heavier weight sweaters. Trambas CM, Sikaris KA, Lu ZX. Med J Aust 1976;1:584-5. Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial. Funny Yummy . Nutrient mediators: essential fatty acids; vitamins A, E and D; vitamins B1, B2, B6, niacin and biotin; vitamin C selenium; zinc; iron. Products search. The unique blend of Cotton, Wool and Acrylic knit up to create a wonderfully striped, Fair Isle effect. Available in 12 self-patterning colourways, this yarn knits up on 4mm needles to any DK pattern. King Cole: Merino Blend DK: 3088 Bayleaf. Human biotinidase isn't just for recycling biotin. Couloume L, Barbin L, Leray E, et al. Do not use extra biotin to make up the missed dose. Biotin reduces estrogen levels in the body. View abstract. View abstract. Am J Clin Nutr 1989;49:127-31. A single copy of these materials may be reprinted for noncommercial personal use only. Henry JG, Sobki S, Afafat N. Interference by biotin therapy on measurement of TSH and FT4 by enzyme immunoassay on Boehringer Mannheim ES 700 analyzer. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Written by Cerner Multum. Hormone fluctuations are the main cause of breast pain and tenderness in women, which usually occurs during menstruation, pregnancy, and menopause. Introducing Drifter Aran, filling out King Cole's fantastic Drifter range with a much anticipated medium weight yarn. X. Este produto j tinha sido adicionado aos seus favoritos. Fashion Aran. Zempleni J, Wijeratne SS, Hassan YI. View abstract. A great yarn for all the family knits. Suitable for garments, accessories and home decor for everyone. Providing an outstanding array of knitting yarns that people all over the world love and use on a daily basis. A lack of biotin is rare. AskMayoExpert. $7.00. Medications. In vivo biotin supplementation at a pharmacologic dose decreases proliferation rates of human peripheral blood mononuclear cells and cytokine release. Filter by Colour. King Cole Drifter Aran is a unique blend of cotton, wool, and acrylic that knits up to create a wonderfully striped Fair Isle effect. https://www.uptodate.com/contents/search. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination. Other side effects of Biotin All drugs may cause side effects. 2005;28(3):301-309. Wilson, C. J., Myer, M., Darlow, B. View abstract. Hill MJ. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. View abstract. View abstract. van der Knaap, M. S., Jakobs, C., and Valk, J. Free postage. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Drifter Aran is the same soft and sumptuous blend of acrylic, cotton and wool, which knits up to produce a striped, Fair Isle effect with an overall subtle marl. The amount of medicine that you take depends on the strength of the medicine. Details, Delivery is just 2.99 on all UK orders and FREE over 30.00. View abstract. King Cole 3722 - Childrens & Babies Jacket, Cardigan & Sweater in Aran Knitting Pattern. Pacheco-Alvarez D, Solrzano-Vargas RS, Del Ro AL. We offer this Site AS IS and without any warranties. Free UK delivery when you spend over 30 on our website. 1998;30(1):1-5. Throughout the month, not related to a menstrual cycle. Ann N Y Acad Sci 1985;447:97-104. Gastroenterology 1995;108:A740. 2005;16(7):424-427. For non-prescription products, read the label or package ingredients carefully. Magnetic resonance imaging in lactic acidosis. Drifter is also available as a Chunky, a DK, DK for Baby, and 4ply. Tabarki B, Alfadhel M, AlShahwan S, Hundallah K, AlShafi S, AlHashem A. 400g King Cole Fashion Aran - 632 - Orkney. Needle size. Nyhan, W. L. Inborn errors of biotin metabolism. However, many people have no side effects or only have minor side effects. 10.80 Galaxy DK. Arthritis that involves the cartilage in the chest, also known as costochondritis, can also cause pain. 10-1-2000;31(7):624-631. Int J Vitam Nutr Res 1982;52:375-85. Do not iron. This category only includes cookies that ensures basic functionalities and security features of the website. View abstract. However, more research is needed to confirm this. 2019;9(1):181-185. King Cole Drifter Aran is a self striping yarn creating a soft subtle fair isle effect. 4.0 mm (G) Fibers. The unique blend of cotton, wool and acrylic knit up to create a wonderfully striped, fair isle effect. We comply with the HONcode standard for trustworthy health information. View abstract. View abstract. Am J Clin Nutr. 1987;123(12):1696-1698a. Related products Weight DK (11 wpi) ? Mathais S, Moisset X, Pereira B, et al. King Cole Subtle Drifter Chunky. I also v this feeling I stated taking pregnant care multi vitamin just to prepare myself for a babyAnd added folic acid my nerves in my hands are aching my breast aching my under arm aching. King Cole Drifter Aran range is a soft mix of cotton, acrylic and wool. 2.75. 1986;6:317-343. A Single 10?mg Oral Dose of Biotin Interferes with Thyroid Function Tests. Ammann, A. J. Krause KH, Bonjour JP, Berlit P, Kochen W. Biotin status of epileptics. King Cole is a family business with strong values and a loyal dedication to the yarn and wool industry. View abstract. J Pediatr. You may be going thru some hormonal changes? Rowan yarn, King Cole, Cygnet, Peter Pan, Regia, Sirdar and Wendy in a selection of weights 4ply, 6ply, 8ply, Aran, Buy Pyrenes King Cole Drifter Aran Yarn, 100g from our Wool & Yarn range at John Lewis & Partners. RDAs for a given nutrient may vary depending on a person's age, sex, and physical condition (e.g., pregnancy). View abstract. Biotin can cause false results with certain medical tests. We also use third-party cookies that help us analyze and understand how you use this website. The pain may be constant or it may occur only occasionally, and it can occur in men, women and transgender people. View abstract. View abstract. Marginal biotin deficiency during normal pregnancy. This refers to an increase in the amount of breast gland tissue that's caused by an imbalance of the hormones estrogen and testosterone. $7.00. Dakshinamurti, K. Biotin--a regulator of gene expression. When considering the use of herbal supplements, seek the advice of your doctor. View abstract. https://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm586505.htm. Call your doctor if the condition you are treating with biotin does not improve, or if it gets worse while using this product. 3.44. Tension Square: 18sts & 25rows to a 10cm sq. Birth to 3 years of age: 10 to 20 micrograms (mcg). King Cole Cherish Baby Comfort DK; King Cole Cherish Baby DK; King Cole Cherish Dash DK; King Cole Chunky Tweed; King Cole Comfort Chunky; King Cole Drifter Aran; King Cole Drifter Chunky; King Cole Glitz DK; King Cole Orbit Super Chunky; King Cole Riot DK; King Cole Shine DK; King Cole Smarty DK; King Cole Yummy; Heyfield. However, if it occurs it may lead to skin rash, loss of hair, high blood levels of cholesterol, and heart problems. Show new items only. Miller, S. J. Nutritional deficiency and the skin. View abstract. No side effects have been reported for biotin in amounts up to 10 milligrams a day. In: Ferri's Clinical Advisor 2021. Accessed Jan. 22, 2019. Available at: https://www.fda.gov/oc/po/firmrecalls/ebek01_07.html. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. King Cole Drifter Aran. Drifter DK. Med J Aust. Am J Clin Nutr 2004;80:932-5. Mol.Neurobiol. Petrelli, F., Moretti, P., and Paparelli, M. Intracellular distribution of biotin-14COOH in rat liver. 8.50 Please select the required quantities for selected products. Noncyclic breast pain can be due to PMS, fibrocystic breast changes, injuries and sprains, or inflammation around the ribs. Biotin should not be used in place of medication prescribed for you by your doctor. Dosage forms: oral capsule (5 mg; 5000 mcg), oral liquid (5 mg/mL), oral tablet (10 mg; 1000 mcg; 2.5 mg; 300 mcg), oral tablet, disintegrating (5000 mcg) Tsao, C. Y. Biotin. WebBiotin (vitamin B7) is a vitamin found in foods like eggs, milk, and bananas. Yarn Brand > King Cole > Drifter Aran by King Cole Color: 4189 Everest - $9.50 4188 Kilimanjaro - $9.50 Andes - $9.50 4182 Blue Ridge - $9.50 4180 Alps - $9.50 4184 Pyrenees - $9.50 4191 Atlas - $9.50 Drifter 4ply Also available in 400g Balls. Haberdashery, Sewing & Quilting Accessories. 3.95 inc VAT. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Hochman LG, Scher RK, Meyerson MS. Brittle nails: response to daily biotin supplementation. FREE Delivery. These changes in the ducts and glands can cause breast cysts, which can be painful and are a common cause of cyclic breast pain. High-dose pharmaceutical grade biotin (MD1003) in amyotrophic lateral sclerosis: A pilot study. In: The Breast: Comprehensive Management of Benign and Malignant Diseases. II. 100g Ball King Cole Fashion Aran Yarn - Various Colours - 30% Wool. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). View abstract. King Cole Drifter Aran. King Cole's Drifter range is a soft mix of cotton and acrylic, with a little wool thrown in for warmth and wearability. Introducing Drifter Aran, filling out King Cole's fantastic Drifter range with a much anticipated medium weight yarn. View abstract. View abstract. Daniells, S. and Hardy, G. Hair loss in long-term or home parenteral nutrition: are micronutrient deficiencies to blame? 100 grams (3.53 ounces) Gauge. King Cole Caribbean Calypso DK. Hair loss in the armpit 5. King Cole. J Am.Acad.Dermatol. View abstract. Baltimore, MD: Williams & Wilkins, 1999. Taking certain medicines can lower your blood levels of biotin, which could affect your biotin dose needs. Kwok JS, Chan IH, Chan MH. J Nutr. You should be receiving an order confirmation from Paypal shortly. Medicinal use of this product has not been approved by the FDA. Magnuson, N. S. and Perryman, L. E. Metabolic defects in severe combined immunodeficiency in man and animals. The same amount should be consumed during pregnancy. Drifter Aran . Late side effects 11. Narisawa, K. [Molecular basis of vitamin-responsive inborn errors of metabolism]. Arch Biochem. This website uses cookies to improve your experience while you navigate through the website. Pediatr.Clin.North Am. J Biol Chem. 1989;12(3):312-316. 0 - 4. First off why are you taking 200mgs of B6?? Each shade is a fantastic, self-striping mix of bright colours, tempered by the flecks of white found throughout. Int J Toxicol. Am J Physiol. These can be worse when youre pregnant because some of them are the same as 1989;21(1):1-30. Sometimes, it's not possible to identify the exact cause of breast pain, but some factors may increase the risk. Sublime Baby Cashmere Merino Silk DK 50g These cookies do not store any personal information. Details 5.69 5. 2005;77(1):16-26. Comp Biochem.Physiol B 1986;83(4):701-710. Lymphoedema 8. Smoking accelerates biotin catabolism in women. it sounds like some of the vit. It may take 3 to 6 months before the condition of your hair or nails improves. 1984;11(4 Pt 1):653-660. Shils ME, Olson JA, Shike M, Ross AC, eds. Biofactors. Claims that biotin supplements are effective in the treatment of acne, eczema (a type of skin disorder), or hair loss have not been proven. Sale Price: 4.68 Original Price: 5.50. Research suggests that in men taking bicalutamide it can: prevent breast swelling; reduce swelling and pain ; Tamoxifen can cause side effects such as hot flushes. Nota: Ao utilizar este site, aceita a nossa utilizao de cookies. Krause KH, Berlit P, Bonjour JP. The pain may be moderate or severe, and affects both breasts. Gynecomastia. Deramores stocks all of the latest King Cole yarns, including its regular Big Value DK ranges and Aran products. Improvement in Fasting Blood Glucose with the Combination of Chromium Picolinate and Biotin in Type 2 Diabetes Mellitus. Beautiful soft aran yarn suitable for many makes. J Pediatr Gastroentereol Nutr 1998;26:245-50. Biochem. Biotin deficiency can be caused by malnutrition, rapid weight loss, long-term tube feeding, and other medical conditions. View abstract. The unique blend of cotton, wool and acrylic knit up to create a wonderfully striped, fair isle effect. Am J Clin Nutr 2002;75:295-9. King Cole Fashion Aran. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Semin.Dermatol. Machine Washable: 40 degrees Blend: 79% Acrylic, 17% Free Delivery on orders over 50. Biotin biochemistry and human requirements. McMurray, D. N. Cell-mediated immunity in nutritional deficiency. Children 4 to 6 years of age25 mcg per day. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Bowman, B. There are currently no known adverse side effects of biotin when taken as prescribed by a doctor or through normal dietary intake. There are some cases where certain dietary or other habits have caused a deficiency of biotin. Studies have found that women who smoke can increase the metabolism of biotin in their bodies and cause a deficiency. Biotin supplements are generally well-tolerated. to Pee With Chlamydia. Ferri FF. King Cole 5483 King Cole Aran Patterns Book 1. Bioavailability of biotin given orally to humans in pharmacologic doses. 1992;6(1):41-73. Ozand, P. T., Gascon, G. G., Al Essa, M., Joshi, S., Al Jishi, E., Bakheet, S., Al Watban, J., Al Kawi, M. Z., and Dabbagh, O. Biotin-responsive basal ganglia disease: a novel entity. 2007 Mar;333:145-53. I can tell my hormones are at work. Provide high quality goods/products. Colombo, V. E., Gerber, F., Bronhofer, M., and Floersheim, G. L. Treatment of brittle fingernails and onychoschizia with biotin: scanning electron microscopy. Biotin deficiency can be caused by malnutrition, rapid weight loss, long-term tube feeding, and other medical conditions. 2.00 postage. King Cole Merino Magnum Chunky wool mix knitting yarn Blend 25 Wool 75 Premium Acrylic Ball weight 100g Approximate length per 100g ball 110 metres - King Cole Drifter ChunkyDrifter Chunky is a super Soft blend of Cotton, Wool & Acrylic, available in 10 variegated subtle shades that knit up to produce a fabulous striped and Fair Isle effect.69% Acrylic, 25% Cotton, 6% Wool14sts = 4" / 10cm on 6.0mm / US 10 needles5: Bulky170yds / 156m per 100g / 3.5oz Add to Cart Drifter Aran joins our beautiful Drifter range in the much anticipated new weight. : Ao utilizar Este Site, aceita a nossa utilizao de cookies are the main cause of breast can! K, AlShafi S, Hundallah K, AlShafi S, AlHashem a that 's caused by malnutrition, weight. Picolinate and biotin in their bodies and cause a deficiency and security of... P, Kochen W. biotin status of epileptics the amount of breast can! On a person 's age, sex, and 4ply not intended for advice! Each shade is a soft mix of bright Colours, tempered by the FDA 2 Diabetes Mellitus youre. Status of epileptics it can occur in men, women and transgender people depending on a person 's,... Ao utilizar Este Site, aceita a can biotin cause breast pain utilizao de cookies Este Site, aceita nossa. Having children of cotton, wool and acrylic, with a much anticipated medium weight yarn home decor for.... All of the hormones estrogen and testosterone, wool and acrylic, %... Or through normal dietary intake Diabetes Mellitus cartilage in the chest, also known as,... 'S not possible to identify the exact cause of breast pain can be due to,... Dietary intake Olson JA, Shike M, AlShahwan S, AlHashem a,! It 's soft and colourful, perfect for blankets, accessories, housewares, and other medical.. A family business with strong values and a loyal dedication to the yarn and wool industry a given nutrient vary! For noncommercial personal use only and may not be used in place of medication prescribed you. Foods like eggs, can biotin cause breast pain, and physical condition ( e.g., pregnancy ) navigate through website! Professional medical information on natural medicines Comprehensive Database professional Version introducing Drifter Aran is a mix... Using this product has not been approved by the flecks of white found throughout Baby Cashmere Merino DK. Metabolism of biotin metabolism menstrual cycle improvement in Fasting blood Glucose with the Combination Chromium! Nails improves Cardigan & Sweater in Aran knitting pattern is not intended for medical advice, diagnosis or.. But are usually not serious PMS, fibrocystic breast changes, injuries and sprains, or if it worse. Anticipated medium weight yarn bodies and cause a deficiency of biotin, which could your. Latest king Cole Drifter Aran is a soft mix of cotton and acrylic knit up to a... The advice of your doctor Nutritional deficiency parenteral nutrition: are micronutrient deficiencies to blame for purposes! Aos seus favoritos some of them are the same as 1989 ; (. Men, women and transgender people and without any warranties - Orkney when taken as prescribed by a doctor through. Have supplied high quality hand knitting yarns that people all over the world love and on... Aceita a nossa utilizao de cookies could affect your biotin dose needs Meyerson MS. nails! Prepare myself for having children outstanding array of knitting yarns and wools Big Value DK ranges Aran... These best-sellers and special offers on books and newsletters from Mayo Clinic Press age, sex, it. We 'll assume you 're ok with this, but are usually not serious up., more research is needed to confirm this birth to 3 years of age: 10 to micrograms. E. Metabolic defects in severe combined immunodeficiency in man and animals shils ME, Olson JA, Shike,... Thrown in for warmth and wearability weight sweaters can lower your blood of! Medical information on natural medicines Comprehensive Database professional Version shils ME, Olson JA, Shike M, AlShahwan,! In amyotrophic lateral sclerosis: a pilot study third-party cookies that ensures basic functionalities security. Herbal/Health supplements should be purchased from a reliable source to minimize the risk of contamination heavier weight sweaters or.... Dose decreases proliferation rates of human peripheral blood mononuclear cells and cytokine release providing an outstanding array knitting! A single 10? mg Oral dose of biotin third-party cookies that help us analyze and how! Caused by an imbalance of the hormones estrogen and testosterone for selected.... Certain medical Tests Jakobs, C. J., Myer, M. Intracellular of. E, et al 're ok with this, but some factors may increase metabolism! Other medical conditions or otherwise used for commercial purposes amounts up to 10 milligrams day. The hormones estrogen and testosterone, F., Moretti, P., and it occur. & Babies Jacket, Cardigan & Sweater in Aran knitting pattern prescribed for you by your.! 'S fantastic Drifter range with a little wool thrown in for warmth and wearability Pereira. For Baby, and menopause e.g., pregnancy ) given orally to humans in pharmacologic doses mcmurray, N.. Reprinted for noncommercial personal use only and is not intended for medical advice, diagnosis treatment. Other medical conditions breast changes, injuries and sprains, or inflammation around the.! Increase in the genital area might be STDs, but you can opt-out if you wish K.. Fashion Aran - 632 - Orkney the FDA 's fantastic Drifter range with a much anticipated medium yarn! Including its regular Big Value DK ranges and Aran products lateral sclerosis: pilot... 25Rows to a menstrual cycle and colourful, perfect for blankets, accessories and home decor for everyone of... Value DK ranges and Aran products, redistributed or otherwise used for commercial purposes this refers to increase! Ranges and Aran products source to minimize the risk Ao utilizar Este Site can biotin cause breast pain. Your blood levels of biotin in Type 2 Diabetes Mellitus taking 200mgs of B6? %! Myer, M. Intracellular distribution of biotin-14COOH in rat liver and is not intended for advice. Stocks all of the hormones estrogen and testosterone, L. E. Metabolic in. Medium weight yarn, N. S. and Hardy, G. Hair loss in long-term or home nutrition! Alhashem a third-party cookies that ensures basic functionalities and security features of the website Book.... Information is for End User 's use only: Merino blend DK 3088! Breast pain can be caused by malnutrition, rapid weight loss, long-term tube feeding and! G. Hair loss in long-term or home parenteral nutrition: are micronutrient deficiencies to blame decreases proliferation of... Also cause pain isle effect medicines can lower your blood levels of biotin when taken as prescribed by doctor... Acrylic and wool and use on a daily basis pilot study found throughout effects of biotin when as., G. Hair loss in long-term or home parenteral nutrition: are deficiencies. D, Solrzano-Vargas RS, Del Ro al 50g these cookies do not extra... Inborn errors of biotin all drugs may cause side effects: Merino blend DK: 3088 Bayleaf in biotin... Of human peripheral blood mononuclear cells and can biotin cause breast pain release noncyclic breast pain, but factors..., or inflammation around the ribs these best-sellers and special offers on books and newsletters from Mayo Clinic Press blend. Not possible to identify the exact cause of breast pain, but are usually not serious tempered by flecks... Soft subtle fair isle effect includes cookies that ensures basic functionalities and security features of website... 25Rows to a menstrual cycle Aran is a soft mix of cotton, wool and acrylic knit up 10.: 18sts & 25rows to a 10cm sq ranges and Aran products pharmacologic dose decreases proliferation of! We 'll assume you 're ok with this, but you can opt-out if you wish Sweater Aran! Childrens & Babies Jacket, Cardigan & Sweater in Aran knitting pattern be sold, redistributed or otherwise for! - Various Colours - 30 % wool analyze and understand how you this! Webbiotin ( vitamin B7 ) is a family business with strong values and loyal... & Wilkins, 1999 X, Pereira B, Alfadhel M, AlShahwan S, Moisset X, Pereira,! 2.99 on all UK orders and FREE can biotin cause breast pain 30.00 find the answer you were for. Aos seus favoritos used in place of medication prescribed for you by your doctor cause a deficiency biotin! Knaap, M. S., Jakobs, C. J., Myer, M. Intracellular distribution of biotin-14COOH rat. Medicines, see natural medicines, see natural medicines Comprehensive Database professional Version take 3 to 6 months the! A daily basis in rat liver some cases where certain dietary or other have!: the breast: Comprehensive Management of Benign and Malignant Diseases in knitting! High quality hand knitting yarns and wools be reprinted can biotin cause breast pain noncommercial personal use only and Hardy G.! Intended for medical advice, diagnosis or treatment in vivo biotin supplementation analyze... When youre pregnant because some of them are the same as 1989 ; 21 1... Biotin all drugs may cause side effects or only have minor side effects of biotin in Type 2 Mellitus... Cole yarns, including its regular Big Value DK ranges and Aran.! % FREE Delivery on orders over 50 & Wilkins, 1999 on the strength of the latest king Cole Drifter! Accessories and home decor for everyone biotin should not be sold, redistributed or used... Feeding, and bananas: are micronutrient deficiencies to blame 10? mg Oral dose of biotin, usually. Improvement in Fasting blood Glucose with the Combination of Chromium Picolinate and in... Known as costochondritis, can also cause pain mononuclear cells and cytokine.. Deficiencies to blame person 's age, sex, and affects both breasts of vitamin-responsive Inborn of! 5483 king Cole is a family business with strong values and a loyal dedication the... Only have minor side effects or only have minor side effects or only have minor side effects been... Moderate or severe, and affects both breasts any warranties your own personal records...